Quantitative ultrasound monitoring of breast tumor response to chemotherapy by analysis of frequency-dependent attenuation and backscattered power

H. Tadayyon; Lakshmanan Sannachi; G. J. Czarnota

doi:10.1117/12.2043075

20 March 2014 Quantitative ultrasound monitoring of breast tumor response to chemotherapy by analysis of frequency-dependent attenuation and backscattered power

H. Tadayyon, Lakshmanan Sannachi, G. J. Czarnota

Author Affiliations +

Proceedings Volume 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography; 904009 (2014) https://doi.org/10.1117/12.2043075
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

Conventional assessment of tumor response to anti-cancer therapy is based on measurements of tumor size (RECIST criteria). However, these measurements are typically a late indicator of tumor response (detectable after several weeks to a few months). There is currently no method to assess tumor response early in the course of therapy. In this study, quantitative ultrasound (QUS) methods were used to characterize the frequency-dependent attenuation and backscatter properties of treatment responding and non-responding tumors in breast cancer patients receiving neoadjuvant chemotherapy. In addition, we assessed the effects of attenuation correction of the power spectrum on the ability to differentiate between responding and non-responding tumors during the course of treatment.

Citation Download Citation

H. Tadayyon, H. Tadayyon, Lakshmanan Sannachi, Lakshmanan Sannachi, G. J. Czarnota, G. J. Czarnota, "Quantitative ultrasound monitoring of breast tumor response to chemotherapy by analysis of frequency-dependent attenuation and backscattered power", Proc. SPIE 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography, 904009 (20 March 2014); doi: 10.1117/12.2043075; https://doi.org/10.1117/12.2043075

ACCESS THE FULL ARTICLE

PERSONAL SIGN IN
Full access may be available with your subscription

Email or Username Forgot your username?

Password Forgot your password?

Show

Remember Email/Username on this computer

Remember Password

No SPIE account? Create an account
or Institutional Sign In via Shibboleth

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $14.40

Non-members: $18.00 ADD TO CART

Show All Keywords

Keywords/Phrases

Search In:

Publication Years