31 December 2013 Multi-excitation Raman difference spectroscopy based on modified multi-energy constrained iterative deconvolution algorithm
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Abstract
Raman spectroscopy is fast and nondestructive, and it is widely used in chemistry, biomedicine, food safety and other areas. However, Raman spectroscopy is often hampered by strong fluorescence background, especially in food additives detection and biomedicine researching. In this paper, one efficient technique was the multi-excitation Raman difference spectroscopy (MERDS) which incorporated a series of small wavelength-shift wavelengths as excitation sources. A modified multi-energy constrained iterative deconvolution (MMECID) algorithm was proposed to reconstruct the Raman Spectroscopy. Computer simulation and experiments both demonstrated that the Raman spectrum can be well reconstructed from large fluorescence background. The more excitation sources used, the better signal to noise ratio got. However, many excitation sources were equipped on the Raman spectrometer, which increased the complexity of the experimental system. Thus, a trade-off should be made between the number of excitation frequencies and experimental complexity.
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Wenlong Zou, Wenlong Zou, Zhijian Cai, Zhijian Cai, Hongwu Zhou, Hongwu Zhou, Jianhong Wu, Jianhong Wu, } "Multi-excitation Raman difference spectroscopy based on modified multi-energy constrained iterative deconvolution algorithm", Proc. SPIE 9042, 2013 International Conference on Optical Instruments and Technology: Optical Systems and Modern Optoelectronic Instruments, 90421G (31 December 2013); doi: 10.1117/12.2041172; https://doi.org/10.1117/12.2041172
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