Fiber Optic Biosensing Probes For Biomedically Important Compounds

Mark A. Arnold

doi:10.1117/12.945267

21 June 1988 Fiber Optic Biosensing Probes For Biomedically Important Compounds

Mark A. Arnold

Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945267
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

Fiber optic biosensing probes for several bioanalytes of clinical and biomedical importance are described. The development of biosensors based on immobilization of a deaminating enzyme at the tip of a fiber optic ammonia sensor is illustrated with a biosensing probe for urea. In addition, biosensors based on the direct fluorometric detection of reduced nicotinamide adenine dinucleotide (NADH) at the tip of an optical fiber device are presented. Probes for lactate and pyruvate illustrate this concept. Finally, preliminary results from an investigation to prepare NADH sensing probes based on immobilized bacterial luciferase are given.

Citation Download Citation

Mark A. Arnold "Fiber Optic Biosensing Probes For Biomedically Important Compounds", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); https://doi.org/10.1117/12.945267

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