In Vivo Light Dosimetry In Interstitial Photodynamic Therapy

I Driver; J W Feather; P R King; D Gilson; D V Ash; B Dixon

doi:10.1117/12.945350

3 June 1988 In Vivo Light Dosimetry In Interstitial Photodynamic Therapy

I Driver, J W Feather, P R King, D Gilson, D V Ash, B Dixon

Proceedings Volume 0908, Laser Interaction with Tissue; (1988) https://doi.org/10.1117/12.945350
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

A non-invasive isotropic fibre optic probe has been developed and used to determine the penetration depth of 630nm light in tumours of rats and a human patient during interstitial photodynamic therapy. The mean penetration depth of the light and standard error of the mean measured was 1.62 ± 0.18mm for a series of eight animal tumours and 1.99 ± 0.51mm in three human tumour nodules. The apparent penetration depth as observed from the area of illuminated skin at a distance from the tumour was also measured and its relevance to the light dosimetry discussed.

Citation Download Citation

I Driver, J W Feather, P R King, D Gilson, D V Ash, and B Dixon "In Vivo Light Dosimetry In Interstitial Photodynamic Therapy", Proc. SPIE 0908, Laser Interaction with Tissue, (3 June 1988); https://doi.org/10.1117/12.945350

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