5 June 2014 Quantitative simultaneous PET-MR imaging
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Whole-body PET is currently limited by the degradation due to patient motion. Respiratory motion degrades imaging studies of the abdomen. Similarly, both respiratory and cardiac motions significantly hamper the assessment of myocardial ischemia and/or metabolism in perfusion and viability cardiac PET studies. Based on simultaneous PET-MR, we have developed robust and accurate MRI methods allowing the tracking and measurement of both respiratory and cardiac motions during abdominal or cardiac studies. Our list-mode iterative PET reconstruction framework incorporates the measured motion fields into PET emission system matrix as well as the time-dependent PET attenuation map and the position dependent point spread function. Our method significantly enhances the PET image quality as compared to conventional methods.
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Jinsong Ouyang, Jinsong Ouyang, Yoann Petibon, Yoann Petibon, Chuan Huang, Chuan Huang, Timothy G. Reese, Timothy G. Reese, Aleksandra L. Kolnick, Aleksandra L. Kolnick, Georges El Fakhri, Georges El Fakhri, "Quantitative simultaneous PET-MR imaging", Proc. SPIE 9083, Micro- and Nanotechnology Sensors, Systems, and Applications VI, 908325 (5 June 2014); doi: 10.1117/12.2051578; https://doi.org/10.1117/12.2051578

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