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28 May 2014 Detection of illicit drugs in impaired driver saliva by a field-usable SERS analyzer
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Abstract
One of the greatest dangers of drug use is in combination with driving. According to the most recent National Highway Traffic Safety Administration (NHTSA) studies, more than 11% of drivers tested positive for illicit drugs, while 18% of drivers killed in accidents tested positive for illicit, prescription or over-the-counter drugs. Consequently, there is a need for a rapid, noninvasive, roadside drug testing device, similar to the breathalyzers used by law enforcement officials to estimate blood alcohol levels of impaired drivers. In an effort to satisfy this need we have been developing a sampling kit that allows extraction of drugs from 1 mL of saliva and detection by surfaceenhanced Raman spectroscopy using a portable Raman analyzer. Here we describe the development of the sampling kit and present measurements of diazepam at sub μg/mL concentrations measured in ~15 minutes.
© (2014) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chetan Shende, Hermes Huang, and Stuart Farquharson "Detection of illicit drugs in impaired driver saliva by a field-usable SERS analyzer", Proc. SPIE 9107, Smart Biomedical and Physiological Sensor Technology XI, 910709 (28 May 2014); https://doi.org/10.1117/12.2054284
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