Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status

Jeffrey L. Ebersole; Richard J. Kryscio; Charles Campbell; Denis F. Kinane; John T. McDevitt; Nicolaos Christodoulides; Pierre N. Floriano; Craig S. Miller

doi:10.1117/12.2058734

5 June 2014 Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status

Jeffrey L. Ebersole, Richard J. Kryscio, Charles Campbell, Denis F. Kinane, John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, Craig S. Miller

Author Affiliations +

Proceedings Volume 9112, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV; 91120G (2014) https://doi.org/10.1117/12.2058734
Event: SPIE Sensing Technology + Applications, 2014, Baltimore, MD, United States

Abstract

With the advent of an increased emphasis on the potential to utilize biomarkers in saliva for systemic diseases, the issue of existing oral disease is an important consideration that could adversely affect the interpretation of diagnostic results obtained from saliva. We addressed the question does a patient’s oral inflammation status confound biomarker levels used in diagnosis of acute myocardial infarction (AMI). The results demonstrated that multiple serum biomarkers and a few salivary biomarkers reflected the cardiac event. Importantly, oral health of the individual had minimal impact on the validity of the serum or salivary biomarker effectiveness.

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Jeffrey L. Ebersole, Richard J. Kryscio, Charles Campbell, Denis F. Kinane, John T. McDevitt, Nicolaos Christodoulides, Pierre N. Floriano, and Craig S. Miller "Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status", Proc. SPIE 9112, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV, 91120G (5 June 2014); https://doi.org/10.1117/12.2058734

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