We present a theoretical scheme for laser cooling of the colloidal cadmium selenide (CbSe) QDs. The laser cooling
process is based on the anti-Stokes fluorescence observed in QDs. We have considered laser cooling in the system of
identical CdSe QDs laser pumped with energy of photons less than mean fluorescence energy. The dependences of all
parameters of the system on the temperature have been taken into account. Following to our simulation the laser cooling
with temperature drop ~100K can be realised with well technologically developed today passivated CdSe QDs.