8 May 2014 Laser double Doppler flowmeter
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Abstract
The Laser Doppler flowmetry (LDF) is a non-invasive method for estimating the tissular blood flow and speed at a microscopic scale (microcirculation). It is used for medical research as well as for the diagnosis of diseases related to circulatory system tissues and organs including the issues of microvascular flow (perfusion). It is based on the Doppler effect, created by the interaction between the laser light and tissues. LDF measures the mean blood flow in a volume formed by the single laser beam, that penetrate into the skin. The size of this measurement volume is crucial and depends on skin absorption, and is not directly reachable. Therefore, current developments of the LDF are focused on the use of always more complex and sophisticated signal processing methods. On the other hand, laser Double Doppler Flowmeter (FL2D) proposes to use two laser beams to generate the measurement volume. This volume would be perfectly stable and localized at the intersection of the two laser beams. With FL2D we will be able to determine the absolute blood flow of a specific artery. One aimed application would be to help clinical physicians in health care units.
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L. Poffo, L. Poffo, J-M. Goujon, J-M. Goujon, R. Le Page, R. Le Page, J. Lemaitre, J. Lemaitre, M. Guendouz, M. Guendouz, N. Lorrain, N. Lorrain, D. Bosc, D. Bosc, } "Laser double Doppler flowmeter", Proc. SPIE 9129, Biophotonics: Photonic Solutions for Better Health Care IV, 91290X (8 May 2014); doi: 10.1117/12.2052505; https://doi.org/10.1117/12.2052505
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