Wavefront (WF) sensing using Sodium (Na) Laser Guide Stars (LGS) is a key concern for the design of a number of first generation Extremely Large Telescope (ELT) Adaptive Optics (AO) modules. One of the main challenges is the mitigation of the effects induced by extreme LGS spot elongation on the WF measurements. Before the final design studies of the E-ELT instruments, a Na LGS WF sensing on-sky experiment at the E-ELT scale is mandatory to achieve the full validation of the proposed mitigation strategies and their performance. This experiment will provide unique spatial and temporal WF measurements on a true Na LGS, perturbed by the atmospheric turbulence and mesospheric variability. The fine comparative analysis of such data with synchronously acquired WF measurements on at least one natural guide star (NGS) will be fundamental to test a number of algorithms, configurations for spot sampling and truncation and WF reconstruction schemes including multi-LGS configurations. A global error budget for the whole experiment will be derived with time to feed into the numerical simulation and the design of subsequent E-ELT LGS-AO modules. The data produced will be made available to the E-ELT community. We propose to use CANARY, the Multi-Object AO demonstrator installed at the 4.2m WHT which is a modular AO platform, equipped with several NGS WF Sensor (WFS) and Rayleigh multi-LGS unit and WFS. The transportable 20W Sodium laser unit (WLGSU), developed at ESO, will be positioned at a varying distance from the WHT to provide off-axis launching (up to 40m), simulating the whole range of LGS spot elongations obtained on the E-ELT. In such a case, the WHT pupil will represent an off-axis sub-pupil of the main E-ELT pupil. In addition, this experiment will include a Na layer profiler and the capability for open and closed loop operations. The experiment is scheduled before the end of 2016.