2 June 2014 In-situ detection of DNA hybridization with a microfiber Bragg grating biosensor
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Proceedings Volume 9157, 23rd International Conference on Optical Fibre Sensors; 91574Z (2014) https://doi.org/10.1117/12.2059433
Event: OFS2014 23rd International Conference on Optical Fiber Sensors, 2014, Santander, Spain
Abstract
Microfiber Bragg gratings (mFBGs) can be used as cost-effective and relatively simple-to-implement biosensors for monitoring DNA interactions in situ. The sensors are functionalized by a monolayer of poly-L-lysine (PLL) with the specific molecular recognition probe DNA sequences to bind with high specificity to a given target. By recording the wavelength seperation between the two resonant peaks of a single mFBG, the mFBG biosensor is capable of detecting the presence of specific target DNA in situ.
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Dandan Sun, Dandan Sun, Tuan Guo, Tuan Guo, Xiaodong Xie, Xiaodong Xie, Yang Ran, Yang Ran, Yunyun Huang, Yunyun Huang, Bai-Ou Guan, Bai-Ou Guan, } "In-situ detection of DNA hybridization with a microfiber Bragg grating biosensor", Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91574Z (2 June 2014); doi: 10.1117/12.2059433; https://doi.org/10.1117/12.2059433
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