17 August 2014 Plasmonic nanosensors for molecular and functional cancer imaging and therapy (presentation video)
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Gold made materials undergo fascinating changes in physicochemical properties when their size is reduced to nanoscale. This phenomenon has been observed as long as some thousands years ago with many famous examples such as the Roman Lycurgus cup from AD400 that makes nanotechnology an ancient filed of human endeavors. Nowadays, we are studying fundamental properties of gold nanoparticles and their interactions with biological environment with the ultimate goal to harness the nanoscale material properties for improved imaging and therapy of devastating diseases such as cancer. In this talk, I will discuss three interconnected areas of research that are involved in development of plasmonic nanosensors for biomedical applications: (1) synthesis of biocompatible molecular specific gold nanoparticles; (2) studies of mechanisms of nanoparticle interactions with cells and tissues to enable molecular-specific imaging and therapy; and (3) optimization of nanoparticles for clinical translation.
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Konstantin V. Sokolov, Konstantin V. Sokolov, "Plasmonic nanosensors for molecular and functional cancer imaging and therapy (presentation video)", Proc. SPIE 9166, Biosensing and Nanomedicine VII, 91660Y (17 August 2014); doi: 10.1117/12.2064743; https://doi.org/10.1117/12.2064743

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