System of the phase tomography of optically anisotropic polycrystalline films of biological fluids

N. I. Zabolotna; S. V. Pavlov; A. G. Ushenko; A. O. Karachevtsev; V. O. Savich; O. V. Sobko; O. V. Olar

doi:10.1117/12.2061116

27 August 2014 System of the phase tomography of optically anisotropic polycrystalline films of biological fluids

N. I. Zabolotna; S. V. Pavlov; A. G. Ushenko; A. O. Karachevtsev; V. O. Savich; O. V. Sobko; O. V. Olar;

Author Affiliations +

Proceedings Volume 9166, Biosensing and Nanomedicine VII; 916616 (2014) https://doi.org/10.1117/12.2061116
Event: SPIE NanoScience + Engineering, 2014, San Diego, California, United States

Abstract

The theoretical background of azimuthally stable method Jones matrix mapping of histological sections of biopsy of uterine neck on the basis of spatial-frequency selection of the mechanisms of linear and circular birefringence is presented. The comparative results of measuring the coordinate distributions of complex degree of mutual anisotropy formed by fibrillar networks of myosin and collagen fibrils of uterine neck tissue of different pathological states - precancer (dysplasia) and cancer (adenocarcinoma) are shown. The values and ranges of change of the statistical (moments of the 1st - 4th order) parameters of complex degree of mutual anisotropy coordinate distributions are studied. The objective criteria of diagnostics of the pathology and differentiation of its severity degree are determined.

Citation Download Citation

N. I. Zabolotna, S. V. Pavlov, A. G. Ushenko, A. O. Karachevtsev, V. O. Savich, O. V. Sobko, O. V. Olar, "System of the phase tomography of optically anisotropic polycrystalline films of biological fluids", Proc. SPIE 9166, Biosensing and Nanomedicine VII, 916616 (27 August 2014); doi: 10.1117/12.2061116; https://doi.org/10.1117/12.2061116

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