27 August 2014 Morphology manipulation of M13 bacteriophage template for nanostructure assembly
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Abstract
A gold-binding M13 bacteriophage was used as a model system to explore templating of inorganic material on geometrically transformed viruses . Gold-binding filamentous phage were converted to spheroid form with a short chloroform treatment, and the resulting morphology was investigated with electron microscopy. Binding studies revealed that spheroid-shaped gold-binding phage preserved its affinity for gold. Spheroids adhered to a planar substrate assembled clusters or rings of gold nanoparticles. This gold-binding phage served as a demonstration of a highly shape-modifiable viral-template for inorganic materials.
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Tam-Triet Ngo-Duc, Mohammed Shahriar Zaman, Chung-Hee Moon, Elaine D. Haberer, "Morphology manipulation of M13 bacteriophage template for nanostructure assembly", Proc. SPIE 9171, Nanobiosystems: Processing, Characterization, and Applications VII, 91710X (27 August 2014); doi: 10.1117/12.2062417; https://doi.org/10.1117/12.2062417
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