Our recent work on optical two-dimensional coherent spectroscopy (2DCS) of semiconductor materials is reviewed. We present and compare two approaches that are appropriate for the study of semiconductor nanostructures. The first one is based on a non-collinear geometry, where the Four-Wave-Mixing (FWM) signal is detected in the form of a radiated optical field. This approach works for samples with translational symmetry, such as Quantum Wells (QWs), or large and dense ensembles of Quantum Dots (QDs). The second method is based on a collinear geometry, where the FWM is detected in the form of a photocurrent. This second approach enables 2DCS of samples where translational symmetry is broken, such as single QDs, nanowires, or nanotubes, and small ensembles thereof. For each method, we provide an example of experimental results obtained on semiconductor QWs. In particular, it is shown how 2DCS can reveal coherent excitonic coupling between adjacent QWs.