Implementation and characterization of phase-resolved Doppler optical coherence tomography method for flow velocity measurement

Pornthep Pongchalee; Kunakorn Palawong; Panomsak Meemon

doi:10.1117/12.2054267

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2 June 2014 Implementation and characterization of phase-resolved Doppler optical coherence tomography method for flow velocity measurement

Pornthep Pongchalee; Kunakorn Palawong; Panomsak Meemon

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Proceedings Volume 9234, International Conference on Experimental Mechanics 2013 and Twelfth Asian Conference on Experimental Mechanics; 923416 (2014) https://doi.org/10.1117/12.2054267
Event: International Conference on Experimental Mechanics 2013 and the Twelfth Asian Conference on Experimental Mechanics, 2013, Bangkok, Thailand

Abstract

In this work, the system implementation and characterization of a Phase-Resolved Doppler Optical Coherence Tomography (PR-DOCT) is presented. The phase-resolved Doppler technique was implemented on a custom built Frequency Domain OCT (FD-OCT) that was recently developed at Suranaree University of Technology. Utilizing Doppler phase changed relation in a complex interference signal caused by moving samples, PR-DOCT can produce visualization and characterization of flow activity such as blood flow in biological samples. Here we report the performance of the implemented PR-DOCT system in term of the Velocity Dynamic Range (VDR), which is defined by the range from the minimum to the maximum detectable axial velocity. The minimum detectable velocity was quantified from a histogram distribution of phase difference between consecutive depth-scan signals when performing Doppler imaging of a stationary mirror. By applying a Gaussian curve fitting to the histogram, the Full Width at Half Maximum (FWHM) of the fitted curve was measured to represent the detectable minimum flow velocity of the system. The maximum detectable velocity was limited by the phase wrapping of the Doppler signal, which is governed by the acquisition speed of the system. We demonstrate the 3D Doppler imaging and velocity measurement of feed flow phantom using 100% milk pumped through a microfluidic chip by using a syringe pump system.

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Pornthep Pongchalee, Kunakorn Palawong, and Panomsak Meemon "Implementation and characterization of phase-resolved Doppler optical coherence tomography method for flow velocity measurement", Proc. SPIE 9234, International Conference on Experimental Mechanics 2013 and Twelfth Asian Conference on Experimental Mechanics, 923416 (2 June 2014); https://doi.org/10.1117/12.2054267

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