The simulation of light distribution in photodynamic therapy for port wine stains

Shi-Yu Zhang; Xiao-Ming Hu; Ya Zhou

doi:10.1117/12.2071537

18 November 2014 The simulation of light distribution in photodynamic therapy for port wine stains

Shi-Yu Zhang, Xiao-Ming Hu, Ya Zhou

Proceedings Volume 9268, Optics in Health Care and Biomedical Optics VI; 92680K (2014) https://doi.org/10.1117/12.2071537
Event: SPIE/COS Photonics Asia, 2014, Beijing, China

Abstract

Photodynamic Therapy is regarded as the best treatment for port wine stains, which has the main adverse effect of various degrees of pain (mild to moderate) during the illumination. Though the cooling and cold water have been used to reduce such pain, there is still no scientific evidence for these relief. In this paper, a realistic skin model is built to simulate the distribution of light under treatment, which helps control the light dose and temperature, and improve the clinical results. Comparing with the general parallel skin model, a curving stratum basale layer is used in this paper, and various blood vessel configurations such as single and multiple vessels with horizontally and vertically oriented, curve vessels, various vessel diameter and various radius of curvature of stratum basale layer are simulated. The results shows a more realistic modeling for the thermal damage and help to relief the pain in the treatment.

Citation Download Citation

Shi-Yu Zhang, Xiao-Ming Hu, and Ya Zhou "The simulation of light distribution in photodynamic therapy for port wine stains", Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 92680K (18 November 2014); https://doi.org/10.1117/12.2071537

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available