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10 March 2015 Experimental systems for optogenetic control of protein activity with photodissociable fluorescent proteins
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Abstract
Fluorescent Light-inducible Proteins are proteins of interest that have Dronpa domains fused to both termini. In the dark, the Dronpa domains tetramerize and cage the protein, but light induces Dronpa dissociation and activates the protein. Here, we describe four experimental systems for light activation of mammalian cells expressing FLiPs.
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Xin X. Zhou and Michael Z. Lin "Experimental systems for optogenetic control of protein activity with photodissociable fluorescent proteins", Proc. SPIE 9305, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II, 930534 (10 March 2015); https://doi.org/10.1117/12.2081242
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