Translator Disclaimer
20 March 2015 Quantitative assessment of corneal biomechanical properties using optical coherence elastography and a modified Rayleigh Lamb-frequency model
Author Affiliations +
Proceedings Volume 9307, Ophthalmic Technologies XXV; 930719 (2015) https://doi.org/10.1117/12.2079542
Event: SPIE BiOS, 2015, San Francisco, California, United States
Abstract
This study reports the application of a modified Rayleigh-Lamb frequency equation (RLFE) to a noncontact optical coherence elastography (OCE) method for quantitative assessment of the biomechanical properties of a porcine cornea. A focused air-pulse induced an elastic wave in the cornea, which was imaged by a phasestabilized optical coherence tomography (OCT) system. From the displacement data acquired by the OCT system, phase velocities of the mechanical wave were extracted by spectral analysis using a fast Fourier transform. Experiments were conducted on 2% agar phantom samples, and the Young’s moduli were assessed by the Rayleigh-Lamb frequency equation, which was validated using uniaxial mechanical compression testing. The Rayleigh-Lamb frequency equation was then applied to OCE data from a normal porcine cornea, in which the fluid-solid effect was considered. The Young’s modulus of the porcine cornea was measured to be ~60 kPa and the shear viscosity was ~0.33 Pa·s. The combination of OCE and RLFE is a promising noninvasive method for the estimation of the biomechanical properties of the cornea in vivo.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Zhaolong Han, Salavat R. Aglyamov, Jiasong Li, Manmohan Singh, Shang Wang, Srilatha Vantipalli, Chen Wu, Chih-hao Liu, Michael D. Twa, and Kirill V. Larin "Quantitative assessment of corneal biomechanical properties using optical coherence elastography and a modified Rayleigh Lamb-frequency model", Proc. SPIE 9307, Ophthalmic Technologies XXV, 930719 (20 March 2015); doi: 10.1117/12.2079542; https://doi.org/10.1117/12.2079542
PROCEEDINGS
5 PAGES


SHARE
Advertisement
Advertisement
Back to Top