In-vivo human corneal nerve imaging using Fourier-domain OCT

Jun Geun Shin; Byeong Ha Lee; Tae Joong Eom; Ho Sik Hwang

doi:10.1117/12.2078689

12 March 2015 In-vivo human corneal nerve imaging using Fourier-domain OCT

Jun Geun Shin, Byeong Ha Lee, Tae Joong Eom, Ho Sik Hwang

Proceedings Volume 9307, Ophthalmic Technologies XXV; 93071U (2015) https://doi.org/10.1117/12.2078689
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

We have imaged human corneal nerve bundles by using real-time Fourier-domain OCT (FD-OCT). Corneal nerves contribute to the maintenance of healthy ocular surface owing to their trophic influences on the corneal epithelium. The FD-OCT system was based on a swept laser of a 50 kHz sweeping rate and 1.31 μm center wavelength. At the area including sclera, limbus, and cornea, we could successfully get the in-vivo tomograms of the corneal nerve bundles. The scan range was 5 x 5mm. In this study, the A-scan images in each B-scan were realigned to have a flat air-surface boundary in the final B-scan image. With this effort, we could align corneal nerve bundle in a same depth and get the 3D image showing the branched and threadlike corneal nerve bundles.

Citation Download Citation

Jun Geun Shin, Byeong Ha Lee, Tae Joong Eom, and Ho Sik Hwang "In-vivo human corneal nerve imaging using Fourier-domain OCT", Proc. SPIE 9307, Ophthalmic Technologies XXV, 93071U (12 March 2015); https://doi.org/10.1117/12.2078689

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