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12 March 2015 In-vivo human corneal nerve imaging using Fourier-domain OCT
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Proceedings Volume 9307, Ophthalmic Technologies XXV; 93071U (2015)
Event: SPIE BiOS, 2015, San Francisco, California, United States
We have imaged human corneal nerve bundles by using real-time Fourier-domain OCT (FD-OCT). Corneal nerves contribute to the maintenance of healthy ocular surface owing to their trophic influences on the corneal epithelium. The FD-OCT system was based on a swept laser of a 50 kHz sweeping rate and 1.31 μm center wavelength. At the area including sclera, limbus, and cornea, we could successfully get the in-vivo tomograms of the corneal nerve bundles. The scan range was 5 x 5mm. In this study, the A-scan images in each B-scan were realigned to have a flat air-surface boundary in the final B-scan image. With this effort, we could align corneal nerve bundle in a same depth and get the 3D image showing the branched and threadlike corneal nerve bundles.
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Jun Geun Shin, Byeong Ha Lee, Tae Joong Eom, and Ho Sik Hwang "In-vivo human corneal nerve imaging using Fourier-domain OCT", Proc. SPIE 9307, Ophthalmic Technologies XXV, 93071U (12 March 2015); doi: 10.1117/12.2078689;

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