2 March 2015 Optical waveguide biosensor based on cascaded Mach-Zehnder interferometer and ring resonator with Vernier effect
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Abstract
Optical waveguide biosensors based on silicon-on-insulator (SOI) have been extensively investigated owing to its various advantages and many potential applications. In this article, we demonstrate a novel highly sensitive biosensor based on cascaded Mach-Zehnder interferometer (MZI) and ring resonator with the Vernier effect using wavelength interrogation. The experimental results show that the sensitivity reached 1,960 nm/RIU and 19,100 nm/RIU for sensors based on MZI alone and cascaded MZI-ring with Vernier effect, respectively. A biosensing application was also demonstrated by monitoring the interaction between goat and antigoat immunoglobulin G (IgG) pairs. This integrated high sensitivity biosensor has great potential for medical diagnostic applications.
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Xianxin Jiang, Xianxin Jiang, Longhua Tang, Longhua Tang, Jinyan Song, Jinyan Song, Mingyu Li, Mingyu Li, Jian-Jun He, Jian-Jun He, } "Optical waveguide biosensor based on cascaded Mach-Zehnder interferometer and ring resonator with Vernier effect", Proc. SPIE 9310, Frontiers in Biological Detection: From Nanosensors to Systems VII, 931003 (2 March 2015); doi: 10.1117/12.2077943; https://doi.org/10.1117/12.2077943
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