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4 March 2015 Image-guided surgery using near-infrared fluorescent light: from bench to bedside
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Due to its relatively high tissue penetration, near-infrared (NIR; 700-900 nm) fluorescent light has the potential to visualize structures that need to be resected (e.g. tumors, lymph nodes) and structures that need to be spared (e.g. nerves, ureters, bile ducts). Until now, most clinical trials have focused on suboptimal, non-targeted dyes. Although successful, a new era in image-guided surgery has begun by the introduction of tumor-targeted agents. In this paper, we will describe how tumor-targeted NIR fluorescent imaging can be applied in a clinical setting.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Leonora S. F. Boogerd M.D., Henricus J. M. Handgraaf M.D., Cornelis J. H. van de Velde M.D., and Alexander L. Vahrmeijer M.D. "Image-guided surgery using near-infrared fluorescent light: from bench to bedside", Proc. SPIE 9311, Molecular-Guided Surgery: Molecules, Devices, and Applications, 93110U (4 March 2015);

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