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2 March 2015 Nano-particle doped hydroxyapatite material evaluation using spectroscopic polarization sensitive optical coherence tomography
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Bio-ceramics such as hydroxyapatite (HAp) are widely used materials in medical applications, especially as an interface between implants and living tissues. There are many ways of creating structures from HAp like electrochemical assisted deposition, biomimetic, electrophoresis, pulsed laser deposition or sol-gel processing. Our research is based on analyzing the parameters of the sol-gel method for creating thin layers of HAp. In order to achieve this, we propose to use Optical Coherence Tomography (OCT) for non-destructive and non-invasive evaluation. Our system works in the IR spectrum range, which is helpful due to the wide range of nanocomposites being opaque in the VIS range. In order to use our method we need to measure two samples, one which is a reference HAp solution and second: a similar HAp solution with nanoparticles introduced inside. We use silver nanoparticles below 300 nm. The aim of this research is to analyze the concentration and dispersion of nanodopants in the bio-ceramic matrix. Furthermore, the quality of the HAp coating and deposition process repetition have been monitored. For this purpose the polarization sensitive OCT with additional spectroscopic analysis is being investigated. Despite the other methods, which are suitable for nanocomposite materials evaluation, the OCT with additional features seems to be one of the few which belong to the NDE/NDT group. Here we are presenting the OCT system for evaluation of the HAp with nano-particles, as well as HAp manufacturing process. A brief discussion on the usefulness of OCT for bio-ceramics materials examination is also being presented.
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Paulina Strąkowska, Michał Trojanowski, Mateusz Gardas, Maciej J. Głowacki, Maciej Kraszewski, and Marcin R. Strąkowski "Nano-particle doped hydroxyapatite material evaluation using spectroscopic polarization sensitive optical coherence tomography", Proc. SPIE 9312, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIX, 93122X (2 March 2015);

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