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Sponsored by SPIE Co-sponsored by Bayspec Inc. (United States) Coherent Inc. Corning Inc. (United States) Energy Research Company (United States) Fianium Ltd. Hamamatsu Corporation Intuitive Surgical Corporation (United States) LEUKOS (France) NKT Photonics A/S (Denmark) PerkinElmer Inc. (United States) ThorLabs, Inc. Published by SPIE Proceedings of SPIE, 1605-7422, V. 9318 SPIE is an international society advancing an interdisciplinary approach to the science and application of light. The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon. Please use the following format to cite material from this book: Author(s), “Title of Paper,” in Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, edited by Robert R. Alfano, Stavros G. Demos, Proceedings of SPIE Vol. 9318 (SPIE, Bellingham, WA, 2015) Article CID Number. ISSN: 1605-7422 ISBN: 9781628414080 Published by SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA Telephone +1 360 676 3290 (Pacific Time) · Fax +1 360 647 1445 Copyright © 2015, Society of Photo-Optical Instrumentation Engineers. Copying of material in this book for internal or personal use, or for the internal or personal use of specific clients, beyond the fair use provisions granted by the U.S. Copyright Law is authorized by SPIE subject to payment of copying fees. The Transactional Reporting Service base fee for this volume is $18.00 per article (or portion thereof), which should be paid directly to the Copyright Clearance Center (CCC), 222 Rosewood Drive, Danvers, MA 01923. Payment may also be made electronically through CCC Online at copyright.com. Other copying for republication, resale, advertising or promotion, or any form of systematic or multiple reproduction of any material in this book is prohibited except with permission in writing from the publisher. The CCC fee code is 1605-7422/15/$18.00. Printed in the United States of America. Publication of record for individual papers is online in the SPIE Digital Library. Paper Numbering: Proceedings of SPIE follow an e-First publication model, with papers published first online and then in print. Papers are published as they are submitted and meet publication criteria. A unique citation identifier (CID) number is assigned to each article at the time of the first publication. Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online, print, and electronic versions of the publication. SPIE uses a six-digit CID article numbering system in which:
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Conference CommitteeSymposium Chairs
Program Track Chairs
Conference Chairs
Conference Program Committee
Session Chairs
IntroductionThe Optical Biopsy XIII conference, part of the SPIE Photonics West BiOS symposium, was held 10–11 February 2015, in San Francisco. The conference consisted of six sessions and hosted 25 oral presentations, with 14 of these from international contributors, and also included 10 poster presentations. The quality of the presentations was very high and the sessions were well attended. The speakers were informative, engaging, and knowledgeable, thus ensuring a very rewarding event, especially for the students. The title of the Optical Biopsy XIII conference this year was followed by the descriptive: “Toward Real-Time Spectroscopic Imaging and Diagnosis” in order to encompass the focus area of this conference. As a result, about 70 percent of the oral presentations dealt with rapid evaluation or disease detection at the tissue level. Most presentations were concentrated in three main thematic areas: a) fluorescence, time-resolved fluorescence and multispectral imaging; b) light scattering methods including Raman scattering and polarization methods, and; c) the development of new methods and instrumentation or advancements of existing methods. Last year, we discussed that “optical metabolomics” may be a future growth area in the field of optical biopsy. There were two presentations that focused on this area, both providing very promising results. We hope to see more submissions in this area next year. The rapid assessment of surgical specimens may also be another growth area for optical biopsy techniques. Although researchers in optical biopsy have largely focused on developing methods for in vivo detection of disease, the rapid evaluations of excised specimens may be the “first in line” application toward in vivo implementation. The current practice of cryosection for rapid tissue assessment (sectioning of frozen specimens) to perform rapid microscopic analysis of a specimen produces slides of lower quality than formalin fixed paraffin embedded tissue processing. While diagnosis can be rendered in many cases, the tissue is lost and cannot be used for further analysis. Alternatively, optical biopsy methods can provide an even faster method to evaluate the specimen and preserve the specimen for further analysis. We will focus on the potential of optical biopsy methods as a better alternative to cryosection in the next conference. We wish to thank Bayspec Inc., Coherent Inc., Corning Inc., Energy Research Company, Fianium Ltd., Hamamatsu Corp., Intuitive Surgical Corp., LEUKOS, NKT Photonics A/S, PerkinElmer Inc., and Thorlabs, Inc. for their support of Optical Biopsy XIII sessions. We also thank the session chairs, program chairs, and SPIE staff for their help in making this conference successful. Robert R. Alfano Stavros G. Demos |
