13 April 2015 Front Matter: Volume 9318
This PDF file contains the front matter associated with SPIE Proceedings Volume 9318, including the Title Page, Copyright information, Table of Contents, Introduction (if any), and Conference Committee listing.

Sponsored by


Co-sponsored by

Bayspec Inc. (United States)

Coherent Inc.

Corning Inc. (United States)

Energy Research Company (United States)

Fianium Ltd.

Hamamatsu Corporation

Intuitive Surgical Corporation (United States)

LEUKOS (France)

NKT Photonics A/S (Denmark)

PerkinElmer Inc. (United States)

ThorLabs, Inc.

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Proceedings of SPIE, 1605-7422, V. 9318

SPIE is an international society advancing an interdisciplinary approach to the science and application of light.

The papers included in this volume were part of the technical conference cited on the cover and title page. Papers were selected and subject to review by the editors and conference program committee. Some conference presentations may not be available for publication. The papers published in these proceedings reflect the work and thoughts of the authors and are published herein as submitted. The publisher is not responsible for the validity of the information or for any outcomes resulting from reliance thereon.

Please use the following format to cite material from this book:

Author(s), “Title of Paper,” in Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, edited by Robert R. Alfano, Stavros G. Demos, Proceedings of SPIE Vol. 9318 (SPIE, Bellingham, WA, 2015) Article CID Number.

ISSN: 1605-7422

ISBN: 9781628414080

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  • The last two digits indicate publication order within the volume using a Base 36 numbering system employing both numerals and letters. These two-number sets start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B … 0Z, followed by 10-1Z, 20-2Z, etc.

The CID Number appears on each page of the manuscript. The complete citation is used on the first page, and an abbreviated version on subsequent pages.


Numbers in the index correspond to the last two digits of the six-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first four digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B...0Z, followed by 10-1Z, 20-2Z, etc.

  • Agarwal, Asha, 0R

  • Alfano, Robert R., 04, 05, 0U, 0V, 0X, 0Y, 10

  • Anand, Suresh, 08

  • Aruna, Prakasarao, 0J

  • Bae, Sung Chul, 0Z

  • Bidyut, Das, 10

  • Bjorgan, Asgeir, 0G

  • Bohndiek, Sarah E., 0H

  • Bold, Richard, 0B

  • Boydston-White, Susie, 10

  • Buccoliero, Anna Maria, 08

  • Budansky, Yury, 04, 0Y

  • Cheng, Gangge, 10

  • Cicchi, Riccardo, 08

  • Crane, Nicole J., 0W

  • Datta-Mitra, Ananya, 0F

  • Davis, Mandy A., 06

  • De Giorgi, Vincenzo, 08

  • Demos, Stavros, 0F

  • Denstedt, Martin, 0G

  • Desroches, Joannie, 0D

  • Devi, Seema, 0R

  • Dinten, Jean-Marc, 0L

  • Elumalai, Brindha, 0J

  • Fatakdawala, Hussain, 0B

  • Fereidouni, Farzad, 0F

  • Ganesan, Singaravelu, 0J

  • Ghebremedhin, Meron, 0W

  • Giordano, Flavio, 08

  • Gobinet, Cyril, 0L

  • Godavarty, A., 02

  • Gorpas, Dimitris, 0B

  • Gozali, Richard, 05

  • Guerrini, Renzo, 08

  • Guiot, Marie-Christine, 0D

  • He, Yong, 0X

  • Jermyn, Michael, 0D

  • Jung, Y.-J., 02

  • Kanamori, Katsuhiro, 0O

  • Khandavilli, Y., 02

  • Kim, Min Ju, 0Z

  • Kim, Sungho, 0Z

  • Koenig, Anne, 0L

  • Koteeswaran, Dornadula, 0J

  • Kumar, Dinesh, 0Z

  • Kunju, Lakshmi P., 06

  • Larin, Kirill V., 07

  • Lazar, Alexander J., 07

  • Leblond, Frédéric, 0D

  • Lev, Dina C., 07

  • Levenson, Richard, 0F

  • Liu, Cheng-hui, 0X, 10

  • Liu, Chih-Hao, 07

  • Liu, Yulong, 10

  • Luka, Janos, 0W

  • Luthman, A. Siri, 0H

  • Maio, Vincenza, 08

  • Manfait, Michel, 0L

  • Marcu, Laura, 0B

  • Massi, Daniela, 08

  • Mercier, Jeanne, 0D

  • Milanic, Matija, 0G

  • Mok, Kelvin, 0D

  • Nesi, Gabriella, 08

  • Nguyen, Thien An, 05, 0X

  • Paluchowski, Lukasz A., 0G

  • Pandey, Kiran, 0R

  • Pavone, Francesco Saverio, 08

  • Perraut, François, 0L

  • Petrecca, Kevin, 0D

  • Pichette, Julien, 0D

  • Pimpinelli, Nicola, 08

  • Piot, Olivier, 0L

  • Pollock, Raphael E., 07

  • Pradhan, Asima, 0R

  • Pu, Yang, 04, 0U, 0V, 0X, 0Y, 10

  • Qi, Ji, 07

  • Rajasekaran, Ramu, 0J

  • Randeberg, Lise Lyngsnes, 0G

  • Rao, P. N. Someshwara, 02

  • Roig, Blandine, 0L

  • Rossari, Susanna, 08

  • Saint-Arnaud, Karl, 0D

  • Santos, Greggy M., 07

  • Shih, Wei-Chuan, 07

  • Siddiqui, Javed, 06

  • Sordillo, Laura A., 04, 0V, 0Y

  • Sordillo, Peter P., 04, 0Y

  • Sturiale, Alessandro, 08

  • Sudheendran, Narendran, 07

  • Tomlins, Scott A., 06

  • Tonelli, Francesco, 08

  • Wang, Leana, 0X

  • Wang, W. B., 05

  • Wang, Xueding, 06

  • Wei, John T., 06

  • Xu, Guan, 06

  • Yang, Timothy K., 0Z

  • Yesupriya, Shubha, 0W

  • Yong, He, 0X

  • Young, Eric D., 07

  • Zhang, Lin, 10

  • Zhang, Yanhong, 0B

  • Zhou, Lixin, 0X, 10

  • Zhou, Yan, 0X, 10

  • Zhu, Ke, 10

Conference Committee

Symposium Chairs

  • James G. Fujimoto, Massachusetts Institute of Technology (United States)

  • R. Rox Anderson, Wellman Center for Photomedicine, Massachusetts General Hospital (United States) and Harvard School of Medicine (United States)

Program Track Chairs

  • Tuan Vo-Dinh, Fitpatrick Institute for Photonics, Duke University (United States)

  • Anita Mahadevan-Jansen, Vanderbilt University (United States)

Conference Chairs

  • Robert R. Alfano, The City College of New York (United States)

  • Stavros G. Demos, Lawrence Livermore National Laboratory (United States)

Conference Program Committee

  • Irving J. Bigio, Boston University (United States)

  • Nicole J. Crane, Naval Medical Research Center (United States)

  • Zhiwei Huang, National University of Singapore (Singapore)

  • Amir Gandjbakhche, National Institutes of Health (United States)

  • Israel Gannot, Tel Aviv University (Israel)

  • Igor V. Meglinski, University of Otago (New Zealand)

  • Yang Pu, The City College of New York (United States)

  • Milind Rajadhyaksha, Memorial Sloan-Kettering Cancer Center (United States)

  • Kestutis Sutkus, The City College of New York (United States)

  • Siavash Yazdanfar, GE Global Research (United States)

Session Chairs

  • 1 Imaging and Biomarkers I

    Yang Pu, The City College of New York (United States)

    Wubao Wang, The City College of New York (United States)

  • 2 Imaging and Biomarkers II

    Mìiìnd Rajadhyaksha, Memorial Sloan-Kettering Cancer Center (United States)

    Israel Gannot, Tel Aviv University (Israel)

  • 3 Instrumentation and Techniques I

    Stavros G. Demos, Lawrence Livermore National Laboratory (United States)

    Amir Gandjbakhche, National Institutes of Health (United States)

  • 4 Instrumentation and Techniques II

    Igor V. Meglinski, University of Otago (New Zealand)

    Nicole J. Crane, Naval Medical Research Center (United States)

  • 5 Raman Scattering Methods

    Laura A. Sordillo, The City College of New York (United States)

    Lingyan Shi, The City College of New York (United States)

  • 6 Polarization Methods

    Zhiwei Huang, National University of Singapore (Singapore)

    Stavros G. Demos, Lawrence Livermore National Laboratory (United States)


The Optical Biopsy XIII conference, part of the SPIE Photonics West BiOS symposium, was held 10–11 February 2015, in San Francisco. The conference consisted of six sessions and hosted 25 oral presentations, with 14 of these from international contributors, and also included 10 poster presentations. The quality of the presentations was very high and the sessions were well attended. The speakers were informative, engaging, and knowledgeable, thus ensuring a very rewarding event, especially for the students.

The title of the Optical Biopsy XIII conference this year was followed by the descriptive: “Toward Real-Time Spectroscopic Imaging and Diagnosis” in order to encompass the focus area of this conference. As a result, about 70 percent of the oral presentations dealt with rapid evaluation or disease detection at the tissue level. Most presentations were concentrated in three main thematic areas: a) fluorescence, time-resolved fluorescence and multispectral imaging; b) light scattering methods including Raman scattering and polarization methods, and; c) the development of new methods and instrumentation or advancements of existing methods.

Last year, we discussed that “optical metabolomics” may be a future growth area in the field of optical biopsy. There were two presentations that focused on this area, both providing very promising results. We hope to see more submissions in this area next year. The rapid assessment of surgical specimens may also be another growth area for optical biopsy techniques. Although researchers in optical biopsy have largely focused on developing methods for in vivo detection of disease, the rapid evaluations of excised specimens may be the “first in line” application toward in vivo implementation. The current practice of cryosection for rapid tissue assessment (sectioning of frozen specimens) to perform rapid microscopic analysis of a specimen produces slides of lower quality than formalin fixed paraffin embedded tissue processing. While diagnosis can be rendered in many cases, the tissue is lost and cannot be used for further analysis. Alternatively, optical biopsy methods can provide an even faster method to evaluate the specimen and preserve the specimen for further analysis. We will focus on the potential of optical biopsy methods as a better alternative to cryosection in the next conference.

We wish to thank Bayspec Inc., Coherent Inc., Corning Inc., Energy Research Company, Fianium Ltd., Hamamatsu Corp., Intuitive Surgical Corp., LEUKOS, NKT Photonics A/S, PerkinElmer Inc., and Thorlabs, Inc. for their support of Optical Biopsy XIII sessions. We also thank the session chairs, program chairs, and SPIE staff for their help in making this conference successful.

Robert R. Alfano Stavros G. Demos

© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
} "Front Matter: Volume 9318", Proc. SPIE 9318, Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, 931801 (13 April 2015); doi: 10.1117/12.2192360; https://doi.org/10.1117/12.2192360

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