In vivo time-resolved multidistance near infra-red spectroscopy of adult heads: time shift tolerance of measured reflectance to suppress the coupling between absorption and reduced scattering coefficients

T. Tanifuji; D. Sakai

doi:10.1117/12.2077030

5 March 2015 In vivo time-resolved multidistance near infra-red spectroscopy of adult heads: time shift tolerance of measured reflectance to suppress the coupling between absorption and reduced scattering coefficients

T. Tanifuji, D. Sakai

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Proceedings Volume 9319, Optical Tomography and Spectroscopy of Tissue XI; 93191H (2015) https://doi.org/10.1117/12.2077030
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

The absorption and reduced scattering coefficients ( μ_a and μ'_s) of adult heads were determined by multidistance timeresolved reflectance measurements. The finite difference time domain analysis was used to calculate the time-resolved reflectance from adult head models. In vivo time-resolved reflectances of human heads was measured at wavelengths of 680 and 780 nm. By minimizing the objective functions that compare the theoretical and experimental time-resolved reflectances, μ_a and μ'_s of the brains were determined. The results show that the time shift tolerance of measured reflectance for reducing to less than 10% the deviations in μ_a and μ'_sdue to their coupling from the values obtained by optimum time shifts is more than 20 ps at both wavelengths.

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T. Tanifuji and D. Sakai "In vivo time-resolved multidistance near infra-red spectroscopy of adult heads: time shift tolerance of measured reflectance to suppress the coupling between absorption and reduced scattering coefficients", Proc. SPIE 9319, Optical Tomography and Spectroscopy of Tissue XI, 93191H (5 March 2015); https://doi.org/10.1117/12.2077030

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KEYWORDS

Reflectivity

Head

Sensors

Absorption

Scattering

Tolerancing

Picosecond phenomena

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