Paper
5 March 2015 Photobiostimulation on chondrocytes proliferation in different concentration of fetal bovine serum under low-level laser irradiation
Liqin Zheng, Yuhua Wang, Caimin Qiu, Jianlin Chen, Hongqin Yang, Yanding Zhang, Shusen Xie
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Abstract
The aim of this in vitro study was to evaluate the influence of low-level laser irradiation (LLLI) on the chondrocytes proliferation cultured in different concentration of fetal bovine serum (FBS) using 658 nm, 785 nm and 830 nm diode lasers. The role of energy density (10-70 mJ·cm-2) on chondrocytes proliferation following irradiation with 658 nm laser for 2 days was firstly investigated to find out the best laser energy density. Then the effect of LLLI on the proliferation of chondrocytes cultured with fetal bovine serum at 0%, 2%, 5% and 10% was also evaluated. The results showed that there was no or little photobiostimulation on the proliferation of chondrocytes cultured with 0% FBS and 10% FBS; the cell proliferation at 2% and 5% FBS was significantly modulated by LLLI.
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Liqin Zheng, Yuhua Wang, Caimin Qiu, Jianlin Chen, Hongqin Yang, Yanding Zhang, and Shusen Xie "Photobiostimulation on chondrocytes proliferation in different concentration of fetal bovine serum under low-level laser irradiation", Proc. SPIE 9321, Optical Interactions with Tissue and Cells XXVI, 932111 (5 March 2015); https://doi.org/10.1117/12.2078810
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KEYWORDS
Laser irradiation

Absorbance

Fetus

Laser energy

Modulation

In vitro testing

Laser applications

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