11 March 2015 Realistic photoacoustic image simulations of collections of solid spheres using linear array transducer
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Abstract
A methodology for simulating photoacoustic (PA) images of samples with solid spherical absorbers acquired using linear array transducer is described. Two types of numerical phantoms (i.e., polystyrene beads suspended in agar medium) of two different size regimes were imaged with a 40 MHz linear array transducer utilizing this approach. The frequency domain features and statistics of the simulated signals were quantified for tissue characterization. The midband fit at 40 MHz was found to be about 35 dB higher for the sample with larger beads (radius ~7.36 μm) than that of the sample with smaller particles (radius ~ 1.77 μm). The scale parameter of the generalized gamma distribution function was found to be nearly 51 times greater for the former sample compared to the latter sample. The method developed here shows potential to be used a s a fast simulation tool for the PA imaging of collection of absorbers mimicking biological tissue.
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Subhajit Karmakar, Eno Hysi, Michael C. Kolios, Ratan K. Saha, "Realistic photoacoustic image simulations of collections of solid spheres using linear array transducer", Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932339 (11 March 2015); doi: 10.1117/12.2080794; https://doi.org/10.1117/12.2080794
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