11 March 2015 Optical-resolution photoacoustic microscopy of the metabolic rate of oxygen in a mouse renal tumor model
Author Affiliations +
Abstract
We propose using noninvasive longitudinal optical-resolution photoacoustic microscopy (L-ORPAM) to quantify blood flow flux, oxygen saturation (sO2), and thereby the metabolic rate of oxygen (MRO2), for a renal tumor model in the same mouse over weeks to months. Experiments showed that the sO2 difference between the artery and vein decreased greatly due to the arteriovenous shunting effect during tumor growth. Moreover, hypermetabolism was exhibited by an increase in MRO2.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Chenghung Yeh, Chenghung Yeh, Song Hu, Song Hu, Jinyang Liang, Jinyang Liang, Lei Li, Lei Li, Brian Soetikno, Brian Soetikno, Zhi Hong Lu, Zhi Hong Lu, Rebecca E. Sohn, Rebecca E. Sohn, Konstantin Maslov, Konstantin Maslov, Jeffrey M. Arbeit, Jeffrey M. Arbeit, Lihong V. Wang, Lihong V. Wang, } "Optical-resolution photoacoustic microscopy of the metabolic rate of oxygen in a mouse renal tumor model", Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 93233H (11 March 2015); doi: 10.1117/12.2082948; https://doi.org/10.1117/12.2082948
PROCEEDINGS
8 PAGES


SHARE
Back to Top