Video-rate dual polarization multispectral endoscopic imaging

Anne Pigula; Neil T. Clancy; Shobhit Arya; George B. Hanna M.D.; Daniel S. Elson

doi:10.1117/12.2079726

10 March 2015 Video-rate dual polarization multispectral endoscopic imaging

Anne Pigula, Neil T. Clancy, Shobhit Arya, George B. Hanna M.D., Daniel S. Elson

Proceedings Volume 9333, Biomedical Applications of Light Scattering IX; 93330N (2015) https://doi.org/10.1117/12.2079726
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Cancerous and precancerous growths often exhibit changes in scattering, and therefore depolarization, as well as collagen breakdown, causing changes in birefringent effects. Simple difference of linear polarization imaging is unable to represent anisotropic effects like birefringence, and Mueller polarimetry is time-consuming and difficult to implement clinically. This work presents a dual-polarization endoscope to collect co- and cross-polarized images for each of two polarization states, and further incorporates narrow band detection to increase vascular contrast, particularly vascular remodeling present in diseased tissue, and provide depth sensitivity. The endoscope was shown to be sensitive to both isotropic and anisotropic materials in phantom and in vivo experiments.

Citation Download Citation

Anne Pigula, Neil T. Clancy, Shobhit Arya, George B. Hanna M.D., and Daniel S. Elson "Video-rate dual polarization multispectral endoscopic imaging", Proc. SPIE 9333, Biomedical Applications of Light Scattering IX, 93330N (10 March 2015); https://doi.org/10.1117/12.2079726

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