18 March 2015 Performance comparison of breast imaging modalities using a 4AFC human observer study
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Abstract
This work compares the visibility of spheres and simulated masses in 2D-mammography and tomosynthesis systems using human observer studies. Performing comparison studies between breast imaging systems poses a number of practical challenges within a clinical environment. We therefore adopted a simulation approach which included synthetic breast blocks, a validated lesion simulation model and a set of validated image modelling tools as a viable alternative to clinical trials. A series of 4-alternative forced choice (4AFC) human observer experiments has been conducted for signal detection tasks using masses and spheres as targets. Five physicists participated in the study viewing images with a 5mm target at a range of contrast levels and 60 trials per experimental condition. The results showed that tomosynthesis has a lower threshold contrast than 2D-mammography for masses and spheres, and that detection studies using spheres may produce overly-optimistic threshold contrast values.
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Premkumar Elangovan, Alaleh Rashidnasab, Alistair Mackenzie, David R. Dance, Kenneth C. Young, Hilde Bosmans, William P. Segars, Kevin Wells, "Performance comparison of breast imaging modalities using a 4AFC human observer study", Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 94121T (18 March 2015); doi: 10.1117/12.2081878; https://doi.org/10.1117/12.2081878
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