Image registration using stationary velocity fields parameterized by norm-minimizing Wendland kernel

Akshay Pai; Stefan Sommer; Lauge Sørensen; Sune Darkner; Jon Sporring; Mads Nielsen

doi:10.1117/12.2076469

20 March 2015 Image registration using stationary velocity fields parameterized by norm-minimizing Wendland kernel

Akshay Pai, Stefan Sommer, Lauge Sørensen, Sune Darkner, Jon Sporring, Mads Nielsen

Proceedings Volume 9413, Medical Imaging 2015: Image Processing; 941335 (2015) https://doi.org/10.1117/12.2076469
Event: SPIE Medical Imaging, 2015, Orlando, Florida, United States

Abstract

Interpolating kernels are crucial to solving a stationary velocity field (SVF) based image registration problem. This is because, velocity fields need to be computed in non-integer locations during integration. The regularity in the solution to the SVF registration problem is controlled by the regularization term. In a variational formulation, this term is traditionally expressed as a squared norm which is a scalar inner product of the interpolating kernels parameterizing the velocity fields. The minimization of this term using the standard spline interpolation kernels (linear or cubic) is only approximative because of the lack of a compatible norm. In this paper, we propose to replace such interpolants with a norm-minimizing interpolant - the Wendland kernel which has the same computational simplicity like B-Splines. An application on the Alzheimer's disease neuroimaging initiative showed that Wendland SVF based measures separate (Alzheimer's disease v/s normal controls) better than both B-Spline SVFs (p<0.05 in amygdala) and B-Spline freeform deformation (p<0.05 in amygdala and cortical gray matter).

Citation Download Citation

Akshay Pai, Stefan Sommer, Lauge Sørensen, Sune Darkner, Jon Sporring, and Mads Nielsen "Image registration using stationary velocity fields parameterized by norm-minimizing Wendland kernel", Proc. SPIE 9413, Medical Imaging 2015: Image Processing, 941335 (20 March 2015); https://doi.org/10.1117/12.2076469

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