20 March 2015 Prognosis of intervertebral disc loss from diagnosis of degenerative disc disease
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Degenerative Disc Disease (DDD) is one of the most common causes of low back pain, and is a major factor in limiting the quality of life of an individual usually as they enter older stages of life, the disc degeneration reduces the shock absorption available which in turn causes pain. Disc loss is one of the central processes in the pathogenesis of DDD. In this study, we investigated whether the image texture features quantified from magnetic resonance imaging (MRI) could be appropriate markers for diagnosis of DDD and prognosis of inter-vertebral disc loss. The main objective is to use simple image based biomarkers to perform prognosis of spinal diseases using non-invasive procedures. Our results from 65 subjects proved the higher success rates of the combination marker compared to the individual markers and in the future, we will extend the study to other spine regions to allow prognosis and diagnosis of DDD for a wider region.
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S. Li, S. Li, A. Lin, A. Lin, K. Tay, K. Tay, W. Romano, W. Romano, Said Osman, Said Osman, "Prognosis of intervertebral disc loss from diagnosis of degenerative disc disease", Proc. SPIE 9414, Medical Imaging 2015: Computer-Aided Diagnosis, 94143E (20 March 2015); doi: 10.1117/12.2082727; https://doi.org/10.1117/12.2082727

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