17 March 2015 Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study
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Abstract
Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.
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Jason Zalev, Jason Zalev, Bryan Clingman, Bryan Clingman, Don Herzog, Don Herzog, Tom Miller, Tom Miller, Michael Ulissey, Michael Ulissey, A. Thomas Stavros, A. Thomas Stavros, Alexander Oraevsky, Alexander Oraevsky, Philip Lavin, Philip Lavin, Kenneth Kist, Kenneth Kist, N. Carol Dornbluth, N. Carol Dornbluth, Pamela Otto, Pamela Otto, } "Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study", Proc. SPIE 9419, Medical Imaging 2015: Ultrasonic Imaging and Tomography, 941909 (17 March 2015); doi: 10.1117/12.2081679; https://doi.org/10.1117/12.2081679
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