19 March 2015 Inhomogeneity detection in diffuse optical imaging using conformal mapping
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Abstract
A new method of an optical inhomogeneity detection in strongly scattering media having optical properties of biological tissue Time-Resolved Diffuse Optical Tomography (TR-DOT) is described. The method is based on preliminary processing of a three-dimensional surfaces obtained from the set of time-resolved data in the Cartesian coordinate system, followed by their conformal transform into surfaces in the cylindrical coordinate system. The key feature of the method is application of Late-Arriving Photons (LAP) diffusely transmitted through turbid objects. (i) LAP of each TPSF (Time Point Spread Function) standardized for a minimum angle; (ii) the resulting normalized function approximated by straight lines; (iii) normalized function is modified with the additional factor, K; (iv) final transform to the cylindrical coordinates.
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A. Yu. Potlov, S. V. Frolov, S. G. Proskurin, "Inhomogeneity detection in diffuse optical imaging using conformal mapping", Proc. SPIE 9448, Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, 944805 (19 March 2015); doi: 10.1117/12.2178303; https://doi.org/10.1117/12.2178303
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