Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue-motion artifacts robustness and decorrelation time - blood vessel characteristics

Lev A. Matveev; Vladimir Y. Zaitsev; Grigory V. Gelikonov; Alexandr L. Matveyev; Alexander A. Moiseev; Sergey Yu. Ksenofontov; Valentin M. Gelikonov; Valentin Demidov; Alex Vitkin

doi:10.1117/12.2179246

19 March 2015 Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue-motion artifacts robustness and decorrelation time - blood vessel characteristics

Lev A. Matveev, Vladimir Y. Zaitsev, Grigory V. Gelikonov, Alexandr L. Matveyev, Alexander A. Moiseev, Sergey Yu. Ksenofontov, Valentin M. Gelikonov, Valentin Demidov, Alex Vitkin

Author Affiliations +

Proceedings Volume 9448, Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics; 94481M (2015) https://doi.org/10.1117/12.2179246
Event: Saratov Fall Meeting 2014, 2014, Saratov, Russian Federation

Abstract

We propose a modification of OCT scanning pattern and corresponding signal processing for 3D visualizing blood microcirculation from complex-signal B-scans. We describe the scanning pattern modifications that increase the methods’ robustness to bulk tissue motion artifacts, with speed up to several cm/s. Based on these modifications, OCT-based angiography becomes more realistic under practical measurement conditions. For these scan patterns, we apply novel signal processing to separate the blood vessels with different decorrelation times, by varying of effective temporal diversity of processed signals.

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Lev A. Matveev, Lev A. Matveev, Vladimir Y. Zaitsev, Vladimir Y. Zaitsev, Grigory V. Gelikonov, Grigory V. Gelikonov, Alexandr L. Matveyev, Alexandr L. Matveyev, Alexander A. Moiseev, Alexander A. Moiseev, Sergey Yu. Ksenofontov, Sergey Yu. Ksenofontov, Valentin M. Gelikonov, Valentin M. Gelikonov, Valentin Demidov, Valentin Demidov, Alex Vitkin, Alex Vitkin, "Scan-pattern and signal processing for microvasculature visualization with complex SD-OCT: tissue-motion artifacts robustness and decorrelation time - blood vessel characteristics", Proc. SPIE 9448, Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, 94481M (19 March 2015); doi: 10.1117/12.2179246; https://doi.org/10.1117/12.2179246

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