13 May 2015 Sensors for isolation of anti-cancer compounds found within marine invertebrates
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Abstract
Highly evolved bacteria living within immobile marine animals are being targeted as a source of antitumor pharmaceuticals. This paper describes 2 electo-optical sensor systems developed for identifying species of tunicates and actinobacteria that live within them. Two stages of identification include 1) a benthic survey apparatus to locate species and 2) a laboratory housed cell analysis platform used to classify their bacterial micro-biome. Marine Optics Sampling- There are over 3000 species of Tunicates that thrive in diverse habitats. We use a system of cameras, GPS and the GPS/photo integration application on a PC laptop to compile a time / location stamp for each image taken during the dive survey. A shape-map of x/y coordinates of photos are stored for later identification and sampling. Flow Cytometers/cell sorters housed at The Medical University of South Carolina and The University of Maryland have been modified to produce low-noise, high signal wave forms used for bacteria analysis. We strive to describe salient contrasts between these two fundamentally different sensor systems. Accents are placed on analog transducers and initial step sensing systems and output.
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Gordon Wiegand, Amanda LaRue, "Sensors for isolation of anti-cancer compounds found within marine invertebrates", Proc. SPIE 9490, Advances in Global Health through Sensing Technologies 2015, 94900Q (13 May 2015); doi: 10.1117/12.2176129; https://doi.org/10.1117/12.2176129
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