14 May 2015 Laser-wakefield accelerators for medical phase contrast imaging: Monte Carlo simulations and experimental studies
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X-ray phase contrast imaging (X-PCi) is a very promising method of dramatically enhancing the contrast of X-ray images of microscopic weakly absorbing objects and soft tissue, which may lead to significant advancement in medical imaging with high-resolution and low-dose. The interest in X-PCi is giving rise to a demand for effective simulation methods. Monte Carlo codes have been proved a valuable tool for studying X-PCi including coherent effects. The laser-plasma wakefield accelerators (LWFA) is a very compact particle accelerator that uses plasma as an accelerating medium. Accelerating gradient in excess of 1 GV/cm can be obtained, which makes them over a thousand times more compact than conventional accelerators. LWFA are also sources of brilliant betatron radiation, which are promising for applications including medical imaging. We present a study that explores the potential of LWFA-based betatron sources for medical X-PCi and investigate its resolution limit using numerical simulations based on the FLUKA Monte Carlo code, and present preliminary experimental results.
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S. Cipiccia, D. Reboredo , Fabio A. Vittoria, G. H. Welsh, P. Grant, D. W. Grant, E. Brunetti, S. M. Wiggins, A. Olivo, D. A. Jaroszynski, "Laser-wakefield accelerators for medical phase contrast imaging: Monte Carlo simulations and experimental studies", Proc. SPIE 9514, Laser Acceleration of Electrons, Protons, and Ions III; and Medical Applications of Laser-Generated Beams of Particles III, 951417 (14 May 2015); doi: 10.1117/12.2178837; https://doi.org/10.1117/12.2178837

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