1 June 2015 A biopsymeter to support the diagnostic procedure of skin samples
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Abstract
We present an infrared biopsymeter to assist pathologists in the diagnosis of melanoma presence in skin biopsies. The designed and realized system combines the features of visual inspection and physical sensing to reduce false positives and false negatives occurring during standard histopathological analyses. The biopsymeter determines the CH2-stretch ratio by infrared absorbance measurements of skin biopsies. Investigations conducted with the biopsymeter shows that malignant melanomas and melanoma metastases have higher CH2-stretch ratio values compared to healthy skin tissues.
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Valeria Fioravanti, Shailendra Chandrashekar, Lukas Brandhoff, Daniela Pucciarelli, Sander van den Driesche, Heimo Breiteneder, Christine Hafner, Michael J. Vellekoop, "A biopsymeter to support the diagnostic procedure of skin samples", Proc. SPIE 9518, Bio-MEMS and Medical Microdevices II, 95180A (1 June 2015); doi: 10.1117/12.2178500; https://doi.org/10.1117/12.2178500
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