1 June 2015 Multifunctional biosensing with three-dimensional plasmonic nanoantennas
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Abstract
A new process for implementing vertical metal nanotubes on a multi-electrode array biosensor is described here. The nanotubes can be fabricated on bulk quartz in precise arrangements and with a high degree of freedom in regards of size, aspect ratio and pitch; furthermore they can be aligned with the electrodes. The nanotubes show good biocompatibility with cultured primary neurons and allow to record extracellular neuronal activity. Moreover, the metal nanotubes present plasmonic features such as high electromagnetic field enhancement and localization; these properties are used to combine spectroscopic analysis to electro-physiological recordings.
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Michele Dipalo, Gabriele C. Messina, Hayder Amin, Fabio Moia, Rosanna La Rocca, Victoria Shalabaeva, Alessandro Maccione, Luca Berdondini, Francesco De Angelis, "Multifunctional biosensing with three-dimensional plasmonic nanoantennas", Proc. SPIE 9518, Bio-MEMS and Medical Microdevices II, 95180B (1 June 2015); doi: 10.1117/12.2178845; https://doi.org/10.1117/12.2178845
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