The present study shows the accurate measurement of non-Newtonian blood velocity profiles at different shear rates in a microchannel using a novel translating-stage optical method. Newtonian fluid velocity profile has been well known to be a parabola, but blood is a non-Newtonian fluid which has a plug flow region at the centerline due to yield shear stress and has different viscosities depending on shear rates. The experimental results were compared at the same flow conditions with the theoretical flow equations derived from Casson non-Newtonian viscosity model in a rectangular capillary tube. And accurate wall shear rate and shear stress were estimated for different flow rates based on these velocity profiles. Also the velocity profiles were modeled and compared with parabolic profiles, concluding that the wall shear rates were at least 1.46-3.94 times higher than parabolic distribution for the same volume flow rate.
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Chang-Beom Kim, Jaeho Lim, Hyobong Hong, J. Yasha Kresh, David M. Wootton, "Novel measurement of blood velocity profile using translating-stage optical method and theoretical modeling based on non-Newtonian viscosity model," Proc. SPIE 9523, International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, 95230I (8 July 2015);