Gallium arsenide based surface plasmon resonance for glucose monitoring

Harshada Patil; Vani Sane; Sriram G.; Indumathi T.S.; Preeta Sharan

doi:10.1117/12.2189668

Translator Disclaimer

17 July 2015 Gallium arsenide based surface plasmon resonance for glucose monitoring

Harshada Patil, Vani Sane, Sriram G., Indumathi T.S., Preeta Sharan

Author Affiliations +

Proceedings Volume 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015); 95242E (2015) https://doi.org/10.1117/12.2189668
Event: International Conference on Optical and Photonic Engineering (icOPEN2015), 2015, Singapore, Singapore

Abstract

The recent trends in the semiconductor and microwave industries has enabled the development of scalable microfabrication technology which produces a superior set of performance as against its counterparts. Surface Plasmon Resonance (SPR) based biosensors are a special class of optical sensors that become affected by electromagnetic waves. It is found that bio-molecular recognition element immobilized on the SPR sensor surface layer reveals a characteristic interaction with various sample solutions during the passage of light. The present work revolves around developing painless glucose monitoring systems using fluids containing glucose like saliva, urine, sweat or tears instead of blood samples. Non–invasive glucose monitoring has long been simulated using label free detection mechanisms and the same concept is adapted. In label-free detection, target molecules are not labeled or altered, and are detected in their natural forms. Label-free detection mechanisms involves the measurement of refractive index (RI) change induced by molecular interactions. These interactions relates the sample concentration or surface density, instead of total sample mass. After simulation it has been observed that the result obtained is highly accurate and sensitive. The structure used here is SPR sensor based on channel waveguide. The tools used for simulation are RSOFT FULLWAVE, MEEP and MATLAB etc.

Citation Download Citation

Harshada Patil, Vani Sane, Sriram G., Indumathi T.S., and Preeta Sharan "Gallium arsenide based surface plasmon resonance for glucose monitoring", Proc. SPIE 9524, International Conference on Optical and Photonic Engineering (icOPEN 2015), 95242E (17 July 2015); https://doi.org/10.1117/12.2189668

ACCESS THE FULL ARTICLE