19 June 2015 In vitro evaluation of ionizing radiation effects in bone tissue by FTIR spectroscopy
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Proceedings Volume 9531, Biophotonics South America; 953118 (2015) https://doi.org/10.1117/12.2181096
Event: SPIE Biophotonics South America, 2015, Rio de Janeiro, Brazil
We verified the changes promoted by ionizing radiation in bone tissue using FTIR. Samples of bovine bone were irradiated using Cobalt-60 with 0.01kGy, 0.1kGy, 1kGy, 15kGy and 75kGy. The effects of ionizing irradiation on chemical structure of bone, were studied considering the sub-bands of amide I, the crystallinity index and relation of organic and inorganic materials. ATR-FTIR spectroscopy showed changes in organic components and in hydroxyapatite crystals organization. High correlation with statistical significance was observed between (amideIII+collagen)/ ν1,ν3PO4, crystallinity and mechanical properties of the samples.
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Denise Maria Zezell, Denise Maria Zezell, Marcelo Noronha Veloso, Marcelo Noronha Veloso, Derly Augusto Dias, Derly Augusto Dias, Rodolfo Politano, Rodolfo Politano, Carolina Benetti, Carolina Benetti, } "In vitro evaluation of ionizing radiation effects in bone tissue by FTIR spectroscopy", Proc. SPIE 9531, Biophotonics South America, 953118 (19 June 2015); doi: 10.1117/12.2181096; https://doi.org/10.1117/12.2181096

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