An approach to OCT-based microvascular imaging using reference-free processing of complex valued B-scans

Lev A. Matveev; Grigory V. Gelikonov; Alexandr L. Matveyev; Alexander A. Moiseev; Sergey Ksenofontov; Valentin M. Gelikonov; Marina A. Sirotkina; Natalia L. Buyanova; Natalia D. Gladkova; Valentin Demidov; Alex Vitkin; Vladimir Yu. Zaitsev

doi:10.1117/12.2184937

20 July 2015 An approach to OCT-based microvascular imaging using reference-free processing of complex valued B-scans

Lev A. Matveev, Grigory V. Gelikonov, Alexandr L. Matveyev, Alexander A. Moiseev, Sergey Ksenofontov, Valentin M. Gelikonov, Marina A. Sirotkina, Natalia L. Buyanova, Natalia D. Gladkova, Valentin Demidov, Alex Vitkin, Vladimir Yu. Zaitsev

Author Affiliations +

Proceedings Volume 9541, Optical Coherence Imaging Techniques and Imaging in Scattering Media; 954106 (2015) https://doi.org/10.1117/12.2184937
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

We describe a modification of a recently proposed unconventional OCT approach to 3D microvasculature imaging based on high-pass filtering of B-scans in the lateral direction. The B-scans are acquired in M-mode-like regime with highly overlapped A-scans. The goal of the described modification is to suppress non-fluid artifacts in the resultant microcirculation images. The modification is based on the amplitude normalization procedure of complex-valued OCT signal before subsequent processing. This allows one to efficiently suppress imaging degradation due to the influence of very bright spots/lines (e.g. from hairs on the surface) and retain images of real flows inside the tissue without any artificial cut-off of the surface signal, or application of pixel-intensity thresholds, or signal classification approaches.

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Lev A. Matveev, Grigory V. Gelikonov, Alexandr L. Matveyev, Alexander A. Moiseev, Sergey Ksenofontov, Valentin M. Gelikonov, Marina A. Sirotkina, Natalia L. Buyanova, Natalia D. Gladkova, Valentin Demidov, Alex Vitkin, and Vladimir Yu. Zaitsev "An approach to OCT-based microvascular imaging using reference-free processing of complex valued B-scans", Proc. SPIE 9541, Optical Coherence Imaging Techniques and Imaging in Scattering Media, 954106 (20 July 2015); https://doi.org/10.1117/12.2184937

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