Results of nevus, papilloma, dermatofibroma, and basal cell skin cancer removal by a 980±10 nm diode laser with "blackened" tip operating in continuous (CW) mode and automatic power control (APC) mode are compared. It was demonstrated that using APC mode decreases the width of collateral damage at removing of these nosological neoplasms of human skin. The mean width of collateral damage reached 0.846±0.139 mm for patient group with nevus removing by 980 nm diode laser operating in CW mode, papilloma - 0.443±0.312 mm, dermatofibroma - 0.923±0.271 mm, and basal cell skin cancer - 0.787±0.325 mm. The mean width of collateral damage reached 0.592±0.197 mm for patient group with nevus removing by 980 nm diode laser operating in APC mode, papilloma - 0.191±0.162 mm, dermatofibroma - 0.476±0.366 mm, and basal cell skin cancer - 0.517±0.374 mm. It was found that the percentage of laser wounds with collateral damage less than 300 μm of quantity of removed nosological neoplasms in APC mode is 50%, that significantly higher than the percentage of laser wounds obtained using CW mode (13.4%).