Fluorescence-guided tumor visualization using a custom designed NIR attachment to a surgical microscope for high sensitivity imaging
(Conference Presentation)

David S. Kittle; Chirag G. Patil M.D.; Adam Mamelak M.D.; Stacey Hansen; Jeff Perry; Laura Ishak; Keith L. Black M.D.; Pramod V. Butte

doi:10.1117/12.2214278

26 April 2016 Fluorescence-guided tumor visualization using a custom designed NIR attachment to a surgical microscope for high sensitivity imaging (Conference Presentation)

David S. Kittle, Chirag G. Patil M.D., Adam Mamelak M.D., Stacey Hansen, Jeff Perry, Laura Ishak, Keith L. Black M.D., Pramod V. Butte

Author Affiliations +

Proceedings Volume 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation; 96900I (2016) https://doi.org/10.1117/12.2214278
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Current surgical microscopes are limited in sensitivity for NIR fluorescence. Recent developments in tumor markers attached with NIR dyes require newer, more sensitive imaging systems with high resolution to guide surgical resection. We report on a small, single camera solution enabling advanced image processing opportunities previously unavailable for ultra-high sensitivity imaging of these agents. The system captures both visible reflectance and NIR fluorescence at 300 fps while displaying full HD resolution video at 60 fps. The camera head has been designed to easily mount onto the Zeiss Pentero microscope head for seamless integration into surgical procedures.

Conference Presentation

Citation Download Citation

David S. Kittle, Chirag G. Patil M.D., Adam Mamelak M.D., Stacey Hansen, Jeff Perry, Laura Ishak, Keith L. Black M.D., and Pramod V. Butte "Fluorescence-guided tumor visualization using a custom designed NIR attachment to a surgical microscope for high sensitivity imaging (Conference Presentation)", Proc. SPIE 9690, Clinical and Translational Neurophotonics; Neural Imaging and Sensing; and Optogenetics and Optical Manipulation, 96900I (26 April 2016); https://doi.org/10.1117/12.2214278

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KEYWORDS

Near infrared

Microscopes

Tumors

Cameras

Head

Luminescence

Visualization

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