Detection techniques for singlet oxygen production during photodynamic therapy
(Conference Presentation)

Buhong Li

doi:10.1117/12.2211266

26 April 2016 Detection techniques for singlet oxygen production during photodynamic therapy (Conference Presentation)

Buhong Li

Proceedings Volume 9694, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXV; 96940H (2016) https://doi.org/10.1117/12.2211266
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Singlet oxygen is widely considered to be the major cytotoxic reactive oxygen species (ROS) generated during photodynamic therapy (PDT). This talk summarizes recent advances and future perspectives in detection techniques for singlet oxygen production, and the advantages and limitations of each technique will be presented. In addition, our custom developed novel configuration of a near-infrared sensitive camera and adaptive optics for in vivo fast imaging of singlet oxygen luminescence around 1270 nm will be highlighted. For clinical PDT application, the challenges for direct measrement of singlet oxygen luminescence will be discussed.

Conference Presentation

Citation Download Citation

Buhong Li "Detection techniques for singlet oxygen production during photodynamic therapy (Conference Presentation)", Proc. SPIE 9694, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXV, 96940H (26 April 2016); https://doi.org/10.1117/12.2211266

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