4 March 2016 A projective surgical navigation system for cancer resection
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Abstract
Near infrared (NIR) fluorescence imaging technique can provide precise and real-time information about tumor location during a cancer resection surgery. However, many intraoperative fluorescence imaging systems are based on wearable devices or stand-alone displays, leading to distraction of the surgeons and suboptimal outcome. To overcome these limitations, we design a projective fluorescence imaging system for surgical navigation. The system consists of a LED excitation light source, a monochromatic CCD camera, a host computer, a mini projector and a CMOS camera. A software program is written by C++ to call OpenCV functions for calibrating and correcting fluorescence images captured by the CCD camera upon excitation illumination of the LED source. The images are projected back to the surgical field by the mini projector. Imaging performance of this projective navigation system is characterized in a tumor simulating phantom. Image-guided surgical resection is demonstrated in an ex-vivo chicken tissue model. In all the experiments, the projected images by the projector match well with the locations of fluorescence emission. Our experimental results indicate that the proposed projective navigation system can be a powerful tool for pre-operative surgical planning, intraoperative surgical guidance, and postoperative assessment of surgical outcome. We have integrated the optoelectronic elements into a compact and miniaturized system in preparation for further clinical validation.
Conference Presentation
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Qi Gan, Qi Gan, Pengfei Shao, Pengfei Shao, Dong Wang, Dong Wang, Jian Ye, Jian Ye, Zeshu Zhang, Zeshu Zhang, Xinrui Wang, Xinrui Wang, Ronald Xu, Ronald Xu, } "A projective surgical navigation system for cancer resection", Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960J (4 March 2016); doi: 10.1117/12.2212232; https://doi.org/10.1117/12.2212232
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