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4 March 2016 Fluorophore-conjugated antibodies for imaging and resection of GI tumors
Author Affiliations +
Abstract
Negative surgical margins are critical to prevent recurrence in cancer surgery. This is because with current technology in many cases negative margins are impossible due the inability of the surgeon to detect the margin. Our laboratory has developed fluorophore-labeled monoclonal antibodies to aid in cancer visualization in orthotopic nude mouse models of human gastrointestinal (GI) cancer in order to achieve negative margins in fluorescence-guided surgery (FGS). The technologies described herein have the potential to change the paradigm of surgical oncology to engender significantly improved outcomes.
Conference Presentation
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Michael Bouvet and Robert M. Hoffman "Fluorophore-conjugated antibodies for imaging and resection of GI tumors", Proc. SPIE 9696, Molecular-Guided Surgery: Molecules, Devices, and Applications II, 96960O (4 March 2016); https://doi.org/10.1117/12.2208811
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14 PAGES + PRESENTATION

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